Das Institut für Klinische Pharmakologie und Toxikologie begrüßt Sie

Portrait Prof. Dr. Reinhold Kreutz

Prof. Dr. Reinhold Kreutz

Auf unseren Seiten finden Sie Informationen zu:



im Bereich der Arzneimitteltherapie,

Forschung und

aktuellen Themen

Aktuelle Publikationen

Bolbrinker J, Zaidi Touis L, Gohlke H, Weisser B, Kreutz R
European guidelines on lifestyle changes for management of hypertension : Awareness and implementation of recommendations among German and European physicians.
Herz 2017; May 22. doi: 10.1007/s00059-017-4575-0. [Epub ahead of print]
Abdel-Hady Algharably E, Beige J, Kreutz R, Bolbrinker J
Effect of UMOD genotype on long-term graft survival after kidney transplantation in patients treated with cyclosporine-based therapy.
Pharmacogenomics 2017; Apr 18. doi: 10.1038/tpj.2017.14. [Epub ahead of print]
Turpie AGG, Mantovani LG, Haas S, Kreutz R, Monje D, Schneider J, van Eickels M, Gebel M, Ageno W
Analysis of patients with deep vein thrombosis switched from standard therapy to rivaroxaban in the non-interventional XALIA study.
Thromb Res 2017; Apr 13;155:23-27. doi: 10.1016/j.thromres.2017.04.001. [Epub ahead of print].
Rekers NV, Flaig TM, Mallat MJ, Spruyt-Gerritse MJ, Zandbergen M, Anholts JD, Bajema IM, Clahsen-van Groningen MC, Yang J, de Fijter JW, Claas FH, Brakemeier S, Lachmann N, Kreutz R, de Heer E, Budde K, Bolbrinker J, Eikmans M
Donor genotype and intragraft expression of CYP3A5 reflect the response to steroid treatment during acute renal allograft rejection.
Transplantation 2016; Dec 6. [Epub ahead of print]
Dräger D, Budnick A, Kuhnert R, Kalinowski S, Könner F, Kreutz R
Pain management intervention targeting nursing staff and general practitioners: Pain intensity, consequences and clinical relevance for nursing home residents.
Geriatr Gerontol Int 2016; Dec 9. doi: 10.1111/ggi.12924. [Epub ahead of print]
Langer S, Kreutz R, Eisenreich A
Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions.
J Nephrol 2016; Dec;29(6):765-773. Epub 2016 Jan 5.
Mielke H, Di Consiglio E, Kreutz R, Partosch F, Testai E, Gundert-Remy U
The importance of protein binding for the in vitro-in vivo extrapolation (IVIVE)-example of ibuprofen, a highly protein-bound substance.
Arch Toxicol 2017; Apr;91(4):1663-1670. doi: 10.1007/s00204-016-1863-z. Epub 2016 Oct 21.
Algharably EA, Filler I, Rosenfeld S, Grabowski K, Kreutz R
Statin intolerance - a question of definition.
Expert Opin Drug Saf 2017; Jan;16(1):55-63. Epub 2016 Sep 27.
Flaig T, Douros A, Bronder E, Klimpel A, Kreutz R, Garbe E
Tocilizumab-induced pancreatitis: case report and review of data from the FDA Adverse Event Reporting System.
J Clin Pharm Ther 2016; Dec;41(6):718-721. doi: 10.1111/jcpt.12456. Epub 2016 Sep 27.
Flaig TM, Budnick A, Kuhnert R, Kreutz R, Dräger D
Physician Contacts and Their Influence on the Appropriateness of Pain Medication in Nursing Home Residents: A Cross-Sectional Study.
Am Med Dir Assoc 2016; Sep 1;17(9):834-8. doi: 10.1016/j.jamda.2016.05.014. Epub 2016 Jun 24.
Weidner C, Steinfath M, Opitz E, Oelgeschläger M, Schönfelder G
Defining the optimal animal model for translational research using gene set enrichment analysis.
EMBO Mol Med 2016; Aug 1;8(8):831-8. doi: 10.15252/emmm.201506025.
Haas S, Holberg G, Kreutz R, Lassen MR, Mantovani L, Haupt V, Vogtländer K, Turpie AG
The effects of timing of prophylaxis, type of anesthesia, and use of mechanical methods on outcome in major orthopedic surgery - subgroup analyses from 17,701 patients in the XAMOS study.
Vasc Health Risk Manag 2016; May 18;12:209-18. doi: 10.2147/VHRM.S100293. eCollection 2016.
Qiu R, Horvath A, Stahlmann R
Effects of four nucleoside analogues used as antiviral agents on rat Sertoli cells (SerW3) in vitro.
Arch Toxicol 2016; Aug;90(8):1975-81. doi: 10.1007/s00204-016-1743-6. Epub 2016 May 25.
Douros A, Schaefer C, Kreutz R, Garbe E
[Pharmacovigilance in Germany : It is about time].
Internist (Berl) 2016; Jun;57(6):616-23. doi: 10.1007/s00108-016-0068-0. German.
Douros A, Jobski K, Kollhorst B, Schink T, Garbe E
Risk of venous thromboembolism in cancer patients treated with epoetins or blood transfusions.
Br J Clin Pharmacol 2016; Sep;82(3):839-848. doi: 10.1111/bcp.13019. Epub 2016 Jun 22.
Hallberg P, Eriksson N, Ibañez L, Bondon-Guitton E, Kreutz R, Carvajal A, Lucena MI, Ponce ES, Molokhia M, Martin J, Axelsson T, Yue QY, Magnusson PK, Wadelius M; EuDAC collaborators
Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population.
Lancet Diabetes Endocrinol 2016; Jun;4(6):507-16. doi: 10.1016/S2213-8587(16)00113-3. Epub 2016 May 3.
Eisenreich A, Bolbrinker J, Leppert U
Tissue Factor: A Conventional or Alternative Target in Cancer Therapy.
Clin Chem 2016; Apr;62(4):563-70. doi: 10.1373/clinchem.2015.241521. Epub 2016 Feb 19. Review.
Vogl S, Steinfath M, Lutz WK, Schönfelder G
Effect of Omeprazole and Dextromethorphan on the Urinary Metabolic Ratio of Flurbiprofen.
Basic Clin Pharmacol Toxicol 2016; Jun;118(6):496-8. doi: 10.1111/bcpt.12536. Epub 2016 Jan 14.
Frombach J, Sonnenburg A, Krapohl BD, Zuberbier T, Stahlmann R, Schreiner M
A novel method to generate monocyte-derived dendritic cells during coculture with HaCaT facilitates detection of weak contact allergens in cosmetics.
Arch Toxicol 2017; Jan;91(1):339-350. doi: 10.1007/s00204-016-1722-y. Erratum in PMID: 27344342.
Ageno W, Mantovani LG, Haas S, Kreutz R, Monje D, Schneider J, van Eickels M, Gebel M, Zell E, Turpie AG
Real life studies and good clinical practice - Authors' reply.
Lancet Haematol 2016; Apr;3(4):e160-1. doi: 10.1016/S2352-3026(16)00027-2.
Ageno W, Mantovani LG, Haas S, Kreutz R, Monje D, Schneider J, van Eickels M, Gebel M, Zell E, Turpie AG
Safety and effectiveness of oral rivaroxaban versus standard anticoagulation for the treatment of symptomatic deep-vein thrombosis (XALIA): an international, prospective, non-interventional study.
Lancet Haematol 2016; Jan;3(1):e12-e21. doi: 10.1016/S2352-3026(15)00257-4. Epub 2015 Dec 8.
Kreutz R, Haas S, Holberg G, Lassen MR, Mantovani LG, Schmidt A, Turpie AG
Rivaroxaban compared with standard thromboprophylaxis after major orthopaedic surgery: co-medication interactions.
Br J Clin Pharmacol 2016; Apr;81(4):724-734. doi: 10.1111/bcp.12836. Epub 2016 Feb 12.
Frohwein TA, Sonnenburg A, Zuberbier T, Stahlmann R, Schreiner M
Unsaturated compounds induce up-regulation of CD86 on dendritic cells in the in vitro sensitization assay LCSA.
Arch Toxicol 2016; Apr;90(4):927-36. doi: 10.1007/s00204-015-1527-4. Epub 2015 May 16.
Pulido-Olmo H, García-Prieto CF, Álvarez-Llamas G, Barderas MG, Vivanco F, Aranguez I, Somoza B, Segura J, Kreutz R, Fernández-Alfonso MS, Ruilope LM, Ruiz-Hurtado G
Role of matrix metalloproteinase (MMP)-9 in chronic kidney disease: a new biomarker of resistant albuminuria.
Clin Sci (Lond) 2016; Apr 1;130(7):525-38. doi: 10.1042/CS20150517. Epub 2016 Jan 5.
Eisenreich A, Langer S, Herlan L, Kreutz R
Regulation of podoplanin expression by microRNA-29b associates with its antiapoptotic effect in angiotensin II-induced injury of human podocytes.
J Hypertens 2016; Feb;34(2):323-31. doi: 10.1097/HJH.0000000000000799.
Lassen MR, Haas S, Kreutz R, Mantovani LG, Holberg G, Turpie AG
Rivaroxaban for Thromboprophylaxis After Fracture-Related Orthopedic Surgery in Routine Clinical Practice.
Clin Appl Thromb Hemost 2016; Mar;22(2):138-46. doi: 10.1177/1076029615607303. Epub 2015 Sep 25.
Douros A, Bronder E, Andersohn F, Klimpel A, Kreutz R, Garbe E, Bolbrinker J
Herb-Induced Liver Injury in the Berlin Case-Control Surveillance Study.
Int J Mol Sci 2016; Jan 15;17(1):pii: E114. doi: 10.3390/ijms17010114.
Budnick A, Kuhnert R, Könner F, Kalinowski S, Kreutz R, Dräger D
Validation of a Modified German Version of the Brief Pain Inventory for Use in Nursing Home Residents with Chronic Pain.
J Pain 2016; Feb;17(2):248-56. doi: 10.1016/j.jpain.2015.10.016. Epub 2015 Nov 18.
Hoeltzenbein M, Beck E, Meixner K, Schaefer C, Kreutz R
Pregnancy outcome after exposure to the novel oral anticoagulant rivaroxaban in women at suspected risk for thromboembolic events: a case series from the German Embryotox Pharmacovigilance Centre.
Clin Res Cardiol 2016; Feb;105(2):117-26. doi: 10.1007/s00392-015-0893-5. Epub 2015 Jul 21.
Wallukat G, Müller J, Haberland A, Berg S, Schulz A, Freyse EJ, Vetter R, Salzsieder E, Kreutz R, Schimke I
Aptamer BC007 for neutralization of pathogenic autoantibodies directed against G-protein coupled receptors: A vision of future treatment of patients with cardiomyopathies and positivity for those autoantibodies.
Atherosclerosis 2016; Jan;244:44-7. doi: 10.1016/j.atherosclerosis.2015.11.001. Epub 2015 Nov 10.

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Heike Negatu

Heike Negatu

Charité - Universitätsmedizin Berlin

CCM: Campus Charité Mitte

Charité Centrum Therapieforschung CC 4

Institut für Klinische Pharmakologie und Toxikologie


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