Das Institut für Klinische Pharmakologie und Toxikologie begrüßt Sie

Portrait Prof. Dr. Reinhold Kreutz

Institutsleitung
Prof. Dr. Reinhold Kreutz

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Institut,

Studium,

Serviceangeboten im Bereich der Arzneimitteltherapie,

Forschung und

aktuellen Themen.

Aktuelle Meldungen

Aktuelle Veranstaltungen

Aktuelle Publikationen

Kreutz R, Scholze J, Douros A
Single-pill triple fixed dose combination therapy with single component drug monitoring in treatment-resistant hypertension: a pilot study.
Curr Vasc Pharmacol 2017; Aug 21. doi: 10.2174/1570161115666170821155555. [Epub ahead of print]
Kreutz R, Persson PB, Kubitza D, Thelen K, Heitmeier S, Schwers S, Becka M, Hemmrich M
Dissociation between the pharmacokinetics and pharmacodynamics of once-daily rivaroxaban and twice-daily apixaban: a randomized crossover study.
J Thromb Haemost 2017; Aug 14. doi: 10.1111/jth.13801. [Epub ahead of print]
Wadelius M, Eriksson N, Kreutz R, Bondon-Guitton E, Ibañez L, Carvajal A, Lucena MI, Sancho Ponce E, Molokhia M, Martin J, Axelsson T, Kohnke H, Yue QY, Magnusson PKE, Bengtsson M, Hallberg P; EuDAC
Sulfasalazine-induced agranulocytosis is associated with the human leukocyte antigen locus.
Clin Pharmacol Ther 2017; Aug 1. doi: 10.1002/cpt.805. [Epub ahead of print]
Pleyer U, Algharably EA, Feist E, Kreutz R
Small molecules as therapy for uveitis: a selected perspective of new and developing agents.
Expert Opin Pharmacother 2017; Sep;18(13):1311-1323. doi: 10.1080/14656566.2017.1361408. Epub 2017 Aug 7.
Schaberg T, Bauer T, Brinkmann F, Diel R, Feiterna-Sperling C, Haas W, Hartmann P, Hauer B, Heyckendorf J, Lange C, Nienhaus A, Otto-Knapp R, Priwitzer M, Richter E, Rumetshofer R, Schenkel K, Schoch OD, Schönfeld N, Stahlmann R
[Tuberculosis Guideline for Adults - Guideline for Diagnosis and Treatment of Tuberculosis including LTBI Testing and Treatment of the German Central Committee (DZK) and the German Respiratory Society (DGP).
Pneumologie 2017; 71(6):325-397. doi: 10.1055/s-0043-105954. Epub 2017 Jun 26. German.
Algharably EAH, Bolbrinker J, Lezius S, Reibis R, Wegscheider K, Völler H, Kreutz R
Uromodulin associates with cardiorenal function in patients with hypertension and cardiovascular disease.
J Hypertens 2017; Jun 8. doi: 10.1097/HJH.0000000000001432. [Epub ahead of print]
Leppert U, Gillespie A, Orphal M, Böhme K, Plum C, Nagorsen K, Berkholz J, Kreutz R, Eisenreich A
The impact of α-Lipoic acid on cell viability and expression of nephrin and ZNF580 in normal human podocytes.
Eur J Pharmacol 2017; Sep 5;810:1-8. doi: 10.1016/j.ejphar.2017.06.013. Epub 2017 Jun 10.
Degen GH, Partosch F, Muñoz K, Gundert-Remy U
Daily uptake of mycotoxins - TDI might not be protective for nursed infants.
Toxicol Lett 2017; Jun 7;277:69-75. doi: 10.1016/j.toxlet.2017.06.002. [Epub ahead of print].
Bolbrinker J, Garbe E, Douros A, Huber M, Bronder E, Klimpel A, Andersohn F, Meyer O, Salama A, Kreutz R
Immobilization and high platelet count are associated with thromboembolic complications in heparin-induced thrombocytopenia.
Pharmacoepidemiol Drug Saf 2017; May 24. doi: 10.1002/pds.4235. [Epub ahead of print]
Bolbrinker J, Zaidi Touis L, Gohlke H, Weisser B, Kreutz R
European guidelines on lifestyle changes for management of hypertension : Awareness and implementation of recommendations among German and European physicians.
Herz 2017; May 22. doi: 10.1007/s00059-017-4575-0. [Epub ahead of print]
Abdel-Hady Algharably E, Beige J, Kreutz R, Bolbrinker J
Effect of UMOD genotype on long-term graft survival after kidney transplantation in patients treated with cyclosporine-based therapy.
Pharmacogenomics 2017; Apr 18. doi: 10.1038/tpj.2017.14. [Epub ahead of print]
Turpie AGG, Mantovani LG, Haas S, Kreutz R, Monje D, Schneider J, van Eickels M, Gebel M, Ageno W
Analysis of patients with deep vein thrombosis switched from standard therapy to rivaroxaban in the non-interventional XALIA study.
Thromb Res 2017; Apr 13;155:23-27. doi: 10.1016/j.thromres.2017.04.001. Epub 2017 Apr 13.
Rekers NV, Flaig TM, Mallat MJ, Spruyt-Gerritse MJ, Zandbergen M, Anholts JD, Bajema IM, Clahsen-van Groningen MC, Yang J, de Fijter JW, Claas FH, Brakemeier S, Lachmann N, Kreutz R, de Heer E, Budde K, Bolbrinker J, Eikmans M
Donor genotype and intragraft expression of CYP3A5 reflect the response to steroid treatment during acute renal allograft rejection.
Transplantation 2016; Sep;101(9):2017-2025. doi: 10.1097/TP.0000000000001584.
Dräger D, Budnick A, Kuhnert R, Kalinowski S, Könner F, Kreutz R
Pain management intervention targeting nursing staff and general practitioners: Pain intensity, consequences and clinical relevance for nursing home residents.
Geriatr Gerontol Int 2016; Dec 9. doi: 10.1111/ggi.12924. [Epub ahead of print]
Langer S, Kreutz R, Eisenreich A
Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions.
J Nephrol 2016; Dec;29(6):765-773. Epub 2016 Jan 5.
Mielke H, Di Consiglio E, Kreutz R, Partosch F, Testai E, Gundert-Remy U
The importance of protein binding for the in vitro-in vivo extrapolation (IVIVE)-example of ibuprofen, a highly protein-bound substance.
Arch Toxicol 2017; Apr;91(4):1663-1670. doi: 10.1007/s00204-016-1863-z. Epub 2016 Oct 21.
Algharably EA, Filler I, Rosenfeld S, Grabowski K, Kreutz R
Statin intolerance - a question of definition.
Expert Opin Drug Saf 2017; Jan;16(1):55-63. Epub 2016 Sep 27.
Flaig T, Douros A, Bronder E, Klimpel A, Kreutz R, Garbe E
Tocilizumab-induced pancreatitis: case report and review of data from the FDA Adverse Event Reporting System.
J Clin Pharm Ther 2016; Dec;41(6):718-721. doi: 10.1111/jcpt.12456. Epub 2016 Sep 27.
Flaig TM, Budnick A, Kuhnert R, Kreutz R, Dräger D
Physician Contacts and Their Influence on the Appropriateness of Pain Medication in Nursing Home Residents: A Cross-Sectional Study.
Am Med Dir Assoc 2016; Sep 1;17(9):834-8. doi: 10.1016/j.jamda.2016.05.014. Epub 2016 Jun 24.
Weidner C, Steinfath M, Opitz E, Oelgeschläger M, Schönfelder G
Defining the optimal animal model for translational research using gene set enrichment analysis.
EMBO Mol Med 2016; Aug 1;8(8):831-8. doi: 10.15252/emmm.201506025.
Haas S, Holberg G, Kreutz R, Lassen MR, Mantovani L, Haupt V, Vogtländer K, Turpie AG
The effects of timing of prophylaxis, type of anesthesia, and use of mechanical methods on outcome in major orthopedic surgery - subgroup analyses from 17,701 patients in the XAMOS study.
Vasc Health Risk Manag 2016; May 18;12:209-18. doi: 10.2147/VHRM.S100293. eCollection 2016.
Qiu R, Horvath A, Stahlmann R
Effects of four nucleoside analogues used as antiviral agents on rat Sertoli cells (SerW3) in vitro.
Arch Toxicol 2016; Aug;90(8):1975-81. doi: 10.1007/s00204-016-1743-6. Epub 2016 May 25.
Douros A, Schaefer C, Kreutz R, Garbe E
[Pharmacovigilance in Germany : It is about time].
Internist (Berl) 2016; Jun;57(6):616-23. doi: 10.1007/s00108-016-0068-0. German.
Douros A, Jobski K, Kollhorst B, Schink T, Garbe E
Risk of venous thromboembolism in cancer patients treated with epoetins or blood transfusions.
Br J Clin Pharmacol 2016; Sep;82(3):839-848. doi: 10.1111/bcp.13019. Epub 2016 Jun 22.
Hallberg P, Eriksson N, Ibañez L, Bondon-Guitton E, Kreutz R, Carvajal A, Lucena MI, Ponce ES, Molokhia M, Martin J, Axelsson T, Yue QY, Magnusson PK, Wadelius M; EuDAC collaborators
Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population.
Lancet Diabetes Endocrinol 2016; Jun;4(6):507-16. doi: 10.1016/S2213-8587(16)00113-3. Epub 2016 May 3.
Eisenreich A, Bolbrinker J, Leppert U
Tissue Factor: A Conventional or Alternative Target in Cancer Therapy.
Clin Chem 2016; Apr;62(4):563-70. doi: 10.1373/clinchem.2015.241521. Epub 2016 Feb 19. Review.
Vogl S, Steinfath M, Lutz WK, Schönfelder G
Effect of Omeprazole and Dextromethorphan on the Urinary Metabolic Ratio of Flurbiprofen.
Basic Clin Pharmacol Toxicol 2016; Jun;118(6):496-8. doi: 10.1111/bcpt.12536. Epub 2016 Jan 14.
Frombach J, Sonnenburg A, Krapohl BD, Zuberbier T, Stahlmann R, Schreiner M
A novel method to generate monocyte-derived dendritic cells during coculture with HaCaT facilitates detection of weak contact allergens in cosmetics.
Arch Toxicol 2017; Jan;91(1):339-350. doi: 10.1007/s00204-016-1722-y. Erratum in PMID: 27344342.
Ageno W, Mantovani LG, Haas S, Kreutz R, Monje D, Schneider J, van Eickels M, Gebel M, Zell E, Turpie AG
Real life studies and good clinical practice - Authors' reply.
Lancet Haematol 2016; Apr;3(4):e160-1. doi: 10.1016/S2352-3026(16)00027-2.
Ageno W, Mantovani LG, Haas S, Kreutz R, Monje D, Schneider J, van Eickels M, Gebel M, Zell E, Turpie AG
Safety and effectiveness of oral rivaroxaban versus standard anticoagulation for the treatment of symptomatic deep-vein thrombosis (XALIA): an international, prospective, non-interventional study.
Lancet Haematol 2016; Jan;3(1):e12-e21. doi: 10.1016/S2352-3026(15)00257-4. Epub 2015 Dec 8.

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Sekretariat

Heike Negatu

Heike Negatu

Charité – Universitätsmedizin Berlin

CCM: Campus Charité Mitte

CharitéCentrum Therapieforschung CC 4

Institut für Klinische Pharmakologie und Toxikologie

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Charitéplatz 1

10117 Berlin

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